Wednesday, August 26, 2020

pet Essays - Anthrozoology, Turtle, Pets, Dog, Life Simulation Games

My Pet OK prefer to carry on with an upbeat and beneficial life? At that point get pets! I should let it be known is difficult to accept that trained creatures can advance mental and physical wellbeing, yet numerous investigations have indicated that they can. Then again, you should locate a pet that is perfect with you or with your way of life. Keeping up great psychological wellness is critical for carrying on with a typical life. Numerous therapists have discovered that patients with outrage the executives issues can be more settled with a pet around the house. At times, only the vibe of a pet in the house can do ponders on the nerves and take out certain irritation. I have discovered that having numerous pets around can be troublesome, however with the difficult work comes fulfillment and joy. By and by, I own two turtles, one canine and one fish; my two turtles are in one tank, so they have organization! In my fish tank, there is a savage fish, which would imperil some other fish in the event that I put more in the tank. Isolating creatures that could do mischief to one another is a decent technique for guaranteeing their wellbeing. Also, you should make sure to invest an equivalent measure of energy with your pets? indeed, even your fish, so one pet doesn't get envious of the other. Many give their darling colleagues names, for example, individuals Stanley, Buddy, and Mikey. By giving pets human names individuals feel progressively associated and agreeable around their creature companions. My dog?s name is Bishop, my two turtles names are Squirmy and Mojo and my fish?s name is Mr. Fish. My flat mate named the canine and I named the fish as a result of the manner in which they are Mojo on the grounds that he?s the greater one and Squirmy in light of the fact that he can never remain still longer than a couple of moments. I named my fish Mr. Fish since I couldn?t truly think about a decent name for him. Individuals a few times are incredibly connected to their pets; many take into account all their impulses. A few people in any event, carry their mutts and felines to pet manicurists and beauticians to spoil their pets. This fixation with their pets can prompt profound seeded agony and anguish when a pet passes on. I can defenatly concur with that regardless of whether its not passing and it?s a vanishing of a creature. Like the second day I had my turtles one got away around 3 am in the first part of the day and I was looking extremely hard for my turtle considering just the repulsive things that could have transpired like the pooch eating him or my flat mate unintentionally stepping on him. It took me two or three hours yet I in the long run discovered my turtle and it was an awful inclination simply searching for him uncertain of what had befallen him. Shockingly the truth of a pet kicking the bucket is very real with the present high ways and progressively bustling boulevards can spell certain fate for our four legged mates. Creatures help their proprietors consistently to live their lives somewhat simpler. I concur that creatures As well as giving, soothe from they give a phenomenal measure of satisfaction and love. Numerous individuals state that creatures can not adore or really comprehend our emotions since they are not delegated people and don't communicate in manners that we can not understand. Shockingly individuals over look the way that people are creatures like some other yet that have been honored with a justifiable methods for correspondence .I trust on the off chance that you are a skeptic in the real insight of creatures that this paper changed your viewpoint. What's more, recollect that individuals are creatures as well!

Saturday, August 22, 2020

Nursing Essay Example | Topics and Well Written Essays - 500 words - 3

Nursing - Essay Example Researchers have determined numerous approaches to treat such a malignant growth and the first includes careful expulsion for instance lumpectomy-evacuation of the tumor mass just and a mastectomy-extraction of the mass just as the tissue in the fringe. At that point there is likewise the strategy for radiation treatment, chemotherapy, hormone treatment and the to wrap things up natural treatment. Cervical malignancy is another kind of disease that is unmistakable among the female sexual orientation particularly in the creating mainlands focusing on for the most part the individuals who are in the age gathering of 40-50 years. Tragically, this sort of malignant growth can be affirmed simply after a Pap smear however interestingly, in the event that it had been recognized during the underlying stage, it could be dealt with. Another gynecological sort of malignant growth is the ovarian tumors. These possess the primary basic threat among US residents. The signs and side effects are principally vaginal dying, torment in back and lower midsection, retching, sickness and loss of weight. The treatment includes chemotherapy, warm treatment and now and then even hysterectomy. The fundamental symptoms are that the patients have a low resistant framework and this infers they are progressively presented to contaminations and different maladies and are truly frail after the chemotherapy. They are given dosages of Interferon alpha and furthermore Leukine following the treatment just as safe framework sponsors. Preventative strategies are methods for forestalling undesirable pregnancy just as guaranteeing a maximal degree of security. Beginning from the most encouraging way, the significant position will be the ordinary sort of condom which consoles both against STD and pregnancy however gives no assurance. The following one is the hormonal pills which arevery viable whenever utilized in the correct manner and the symptom is fundamentally queasiness, cerebral pain and weight gain. There is likewise the intra-uterine gadget which is currently embraced by numerous ladies who discover taking pills troublesome have the significant hindrance

Tuesday, August 11, 2020

15 Books to Celebrate Earth Day

15 Books to Celebrate Earth Day 1. Second Nature by Michael Pollen I think John McConnell was spot-on when he proposed the idea of Earth Day, a day to celebrate the beauty and bounty of our tiny little planet and to advocate for its protection and renewal. Since the first Earth Day in 1970, environmental devastation by the agricultural, chemical, pharmaceutical, and energy industries has only grown worse, but there is hope. The environmental movement is now at its height. Consumers are reconsidering their status as consumers and citizens are joining forces to fight for the restoration of ecological balance and the health of all of earth’s creatures. Here are 15 books that explore that struggle and celebrate the magic of the natural world. 1. Second Nature by Michael Pollen Second Nature is a memoir cum philosophical meditation on gardening. As Pollen wrestles with his unruly Connecticut land patch, he ponders the moral imperatives of compost, the absurdity of America’s obsession with the perfect lawn, and the disconnect between the garden of his suburban childhood imagination and the reality of the natural world. Also be sure to check out Pollen’s The Botany of Desire  and The Omnivore’s Dilemma (my personal favorite). 2. Animal, Vegetable, Miracle by Barbara Kingsolver This celebration of food and farm life is one of my favorite books. It invites readers along on a twelve-month adventure in planting, harvesting, preserving, and eating on Kingsolver’s southern Appalachian farm. It’s an eloquent commentary on the disconnect between nature’s rhythms and modern life, and the power of food to strengthen communal and familial bonds. This latter point is punctuated by the format of the book itself, which features fact-filled sidebars by Kingsolver’s husband, Steven L. Hopp and delicious seasonal recipes by her daughter, Camille. 3. Braiding Sweetgrass by Robin Wall Kimmerer Combining scientific knowhow with a wealth of indigenous wisdom, Kimmerer illustrates how colonialism contributed to our current state of environmental decay and presents a compelling vision for how we can “understand the earth as a gift again” and “make our relations with the world sacred again.” Also read Kimmerer’s Gathering Moss. 4. Frackopoly by Wenonah Hauter This upcoming title from The New Press addresses one of the greatest threats to environmental balance and human health today. Fracking, short for hydraulic fracturing, uses an obscene amount of fresh water, contaminates the ground water it doesn’t use, and, according to Hauter, releases dangerous radiation from shale deposits deep within the earthâ€"all with the purpose of extracting an energy source that further contributes to global warming. Debunking the myths perpetuated by the oil industry, Hauter presents a compelling case for alternative energy. 5. Black Nature, Edited by Camille T. Dungy The genre of nature poetry has long been dominated by white voices, but in this anthology, Dungy compiles 180 nature poems from 93 black poets spanning four centuries and numerous movements, including the Harlem Renaissance, Black Arts Movement, and more. Featured poets include Phillis Wheatley, Rita Dove, Yusef Komunyakaa, Sterling Brown, and Wanda Coleman.   6. The Sixth Extinction by Elizabeth Kolbert Environmental scientists and activists have been warning for decades that humanity’s unsustainable exploitation of natural resources and contribution to ecological imbalance is hurtling us headlong toward a man-made extinction event. Such a future is both terrifying and horribly depressing, but we must take the threat seriously if we are to prevent the catastrophe that is already underway. In this Pulitzer Prize winning book, Kolbert unpacks the scientific and philosophical implications of our current path toward destruction. 7. Silent Spring by Rachel Carson This classic started a public outcry that led to the banning of DDT and launched the environmental movement. It’s a righteous indictment of the chemical industry, and more particularly of pesticides and herbicides, the carcinogenic atrocities that sadly are still found in the garages of most suburban homes. I have no doubt that if Rachel Carson were alive today she would be taking on Monsanto, DuPont, and Dow Chemical. 8. Red by Terry Tempest Williams The desert may not seem like the friendliest of landscapes, but in this evocative collection of stories and essays, Williams celebrates the majesty of America’s Redrock Wilderness and advocates for its preservation. She explores the political aspects of the debate over the use of public and private land along the spiritual immediacy of the desert experience. 9. The Soul of an Octopus by Sy Montgomery It’s easy for most non-sociopathic humans in the Western world to connect with domestic animals on an emotional and even spiritual level, but what about those animals that are far removed from the human habitat? Octopi are not the sort of creature we immediately think of as having a deep intellect and emotional life. We eat them in sushi bars after all. In this journalistic exploration of consciousness, Montgomery challenges our understanding of the animal mind and provides readers with an opportunity to connect more fully with the natural world. 10. Sisters of the Earth, Edited by Lorraine Anderson This wonderful anthology of women’s nature writing features the stories, poems, essays, and journal entries of Emily Dickinson, Alice Walker, Terry Tempest Williams, Willa Cather, and many more. 11. Planet Earth by Alastair Fothergill Planet Earth features 400 stunning photographs of landscapes and creatures around the world. Regardless of whether or not you’ve seen the Emmy Award winning documentary, this companion book will make a welcome addition to your coffee table. 12. A Walk in the Woods by Bill Bryson After returning to America after twenty years in Great Britain, Bill Bryson decided to reacquaint himself with his homeland by hiking the 2,100-mile Appalachian Trail. With his signature wit, humor, and eye for the absurd, he explores the history of the trail, remarks on its beauty, and advocates for its conservation. 13. The Cabaret of Plants by Richard Mabey The Cabaret of Plants explores the relationship between humans and plants across 40,000 years of history. Featuring 35 color illustrations, this book is a must have for the amateur naturalist. Also check out Mabey’s Weeds.   14. Black Faces, White Spaces by Carolyn Finney African Americans are doubtlessly underrepresented in environmental and conservation efforts. In this book, Finney explains how slavery, Jim Crow laws, and racism in general have shaped the African American relationship with nature and envisions new ways for black Americans to participate in the effort to preserve the natural world. 15. The Unsettling of America by Wendell Berry The agricultural industry is one of the greatest contributors to environmental ruin, but agriculture done right could potentially be one of the best tools for healing our broken land, communities, and individuals. In this thoughtful collection of letters, Berry explores the devastating impact of Big Agra and the dangers of our modern culture that demands convenience at the cost of our earthly home. Also read Berry’s Our Only World.

Saturday, May 23, 2020

Business Ethics And Law Legal And Ethical Issues

Legal and Ethical Issues in Business Business ethics and law are fundamental principles that guide the way businesses operate. Business ethics are decided and formed by each company and differ from one company to another. They are the core values that business owners, managers, and employees use to conduct their daily operations. Acting in an ethical way consists of distinguishing between right and wrong and choosing what is right. Business law is all rules and regulations that all businesses should be in compliance with. These laws and regulations indicate how to form and run a business in compliance to state, federal, or local laws. There are repercussions when businesses are found violating laws and regulations, which can include but not limited to fines, incarceration, or seizure of one’s business. Business ethics and laws are used in the workplace daily. Both are very important in running a successful business, but one must identify the difference among them. For instance, businesses have to keep in mind that some things may be ethical, but it doesn’t make it legal and vice versa. Ethics comes from within a person’s moral values on how one should or should not act. Laws are created by governments to protect the citizens. James (2016) insists â€Å"both of them are important from maintaining peace and stability in a society† (para 1). Legal and ethical issues go hand in hand within a business. Laws are made to keep those ethical morals in place. Business owners need toShow MoreRelatedMoral Ethics And Values Based Dilemmas871 Words   |  4 PagesMoral ethics and values-based dilemmas are ethical principles that difficult to handle at a workplace when employees have to choose what is wrong and right according to their own ethics. An effective ethics progra m must complement the values of the organization along with the values in the law. Good ethical behavior for any business is always a fundamental to its success. 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Tuesday, May 12, 2020

PESTLE Analysis for Centre Parcs Essay - 3832 Words

Centre Parc’s A PESTLE Analysis Contents 1. Introduction 2. PESTLE Analysis 2.1. What is PESTLE Analysis 2.2. Political 2.3. Economical 2.4. Social 2.5. Technological 2.6. Legislative 2.7. Environmental 3. Entrepreneurial 4. Conclusion 5. References 1. Introduction Centre Parcs are one of the UKs leading family, self-catering holiday destinations. This report aims to analyse the company using one of the key tools available to guide strategic decision making – A PESTLE Analysis. A good way for companies to establish where they are leading or failing in the competitive market is to perform a PESTLE Analysis’ on themselves. It allows companies to asses a whole list of different factor’s that†¦show more content†¦tax changes, new laws and government policy changes. Managers should not just rely on the PESTLE analysis, it is a tool, a snapshot in time, which will assist in understanding the current factors, it will not determine a direct path in the direction they need to follow to progress the company considerably. When in fact managers most need to judge, into what factors are most likely to change and also which have the greatest impact to them, so in the case of Centre Parc’s they need to consider mostly econ omical and sociological. A way of achieving the relevance of each factor to the company is to rank or score the factors, so there is a clear understanding of which are of most importance and vice versa. As Centre Parc’s has many different villages, this means that it includes many divisions and also brands (Starbucks, and Zilli restaurants), so managers need to concentrate on one specific area within each village. 2.2 Political Political factors are heavily driven by the macro environment, so this includes government policies and broader social issues that Centre Parc’s must be

Wednesday, May 6, 2020

Discovered Biological Functions Of Rna Health And Social Care Essay Free Essays

string(65) " alliance with regard to the chosen nonsubjective map \[ 25 \] \." Recently, the figure of ascertained biological maps of RNA has been increasing. In add-on, the range has been expanded, and therefore RNA is non merely a inactive courier of familial information from Deoxyribonucleic acid to proteins makers as had been thought earlier. It has been found that RNA plays of import functions in all of molecular biological science such as transporting familial information ( messenger RNA ) , construing the codification ( ribosomal RNA ) , and reassigning familial codification ( transfer RNA ) . We will write a custom essay sample on Discovered Biological Functions Of Rna Health And Social Care Essay or any similar topic only for you Order Now It besides performs different maps which include: catalyzing chemical reactions [ 1 ] , [ 2 ] , directing the site specific alteration of RNA bases, commanding cistron look, modulating protein look and helping in protein localisation [ 3 ] , [ 4 ] . The map of RNA molecules determine many diseases caused by RNA viruses. Identifying the secondary construction of RNA molecules is the cardinal key to understand its biological map [ 5 ] . The RNA construction anticipation methods, is tremendously affected by the quality of alignment [ 6 ] . MSA significantly improves the de novo anticipation truth of proteins or RNAs structures [ 7 ] . For illustration, current RNA secondary construction anticipation methods utilizing aligned sequences is win in deriving higher anticipation truth than those utilizing individual sequence [ 8 ] . Multiple sequence alliance ( MSA ) has become widely used in many different countries in bioinformatics. Multiple alliances are present in most of the computational method used in molecular development to assist happening sequences household, predict the secondary or third construction of new sequences, RNA folding, cistron ordinance and polymerase concatenation reaction primer design [ 9 ] , foretelling maps, predict patient ‘s diseases by comparing DNAs of patients in disease find. MSA is the most natural manner to see the relation between sequences by doing an alliance between the primary sequences so that indistinguishable or similar residues will be aligned in columns. That is why this method is so called multiple sequence alliance ( MSA ) . At kernel, all widely MSA tools used to better the alignment quality of initial alliance [ 10 ] . The sequence alliance job can be considered as an optimisation job in which the aim is to maximise a marking map [ 11 ] . One chief challenge with MSA is how to gauge the quality of computer-aligned sequences. An nonsubjective map ( OF ) is required in the optimisation processes to happen the optimum alliance. The pick of nonsubjective map is critically of import in obtaining high quality alliances [ 12 ] . In add-on, OF acts an indispensable function in optimisation algorithms whereby there is a relation between the alliance mark with the mark computed by the alignment quality. MSA optimisation job is NP-complete [ 13-15 ] , which motivates, the research for heuristics [ 16 ] . Over the last decennary, the evolutionary and meta-heuristic are the recent attacks to work out the optimisation job. Consequently, most of practical MSA algorithms are based on heuristics to obtain moderately accurate MSA within moderate computational clip and normally produce quasi-optimal alliance. Many researches solve MSA job as optimisation job by utilizing familial algorithm [ 17, 18 ] , Particle Swarm [ 11 ] , ant settlement [ 19 ] , and Simulated tempering [ 20 ] . MSA job can be resolve as optimisation job based on harmoniousness hunt algorithm [ 21 ] to maximise the nonsubjective map and happen the optimum alliance. The purpose of this paper is to analyze and examined the correlativity of different nonsubjective maps utilizing standard sets of RNA datasets. The most straightforward OF is the sum-of-pairs ( SP ) score [ 3 ] , weight sum-of-pair [ ] , java [ 22 ] , Xstate [ ] and NorMD [ 23 ] . This paper is organized as follows: Section 2 introduce the multiple sequence alliance job. Section 3 explains the different nonsubjective map from the state-of-the-art. Section 4 explains the proposed methodological analysis. The rating and analysis methodological analysis that is used to measure our comparing is explained in Section 5. Last, Section 6 provides the decision and sum-up of the paper. 2.0 Multiple Sequence Alliance A sequence is an ordered list of symbols from a set of alphabet S ( 20 amino acids for protein and 4 bases for RNA/DNA ) . In bioinformatics, a RNA sequence is written as s = AUUUCUGUAA. It is a twine over the set S of bases symbols Adenine ( A ) , Cytosine ( C ) , Guanine ( G ) and Uracil ( U ) : S = [ A, C, G, U ] . Alignment is a method to set up the sequences one over the other in a manner to demo the matching and mismatching between residues. A column, which has lucifer residues, shows no mutant is go oning. Whereas, the column with mismatch symbols shows that several mutant events are go oning. To better the alliance mark, the character â€Å" – † is used to match to a infinite introduced in the sequence. This infinite is normally called a spread. The spread is viewed as interpolation in one sequence and omission in the other. A mark is used to mensurate the alliance public presentation. The highest mark one is the best alliance. For lucidity ‘s interest, the generic MSA job is expressed with the following declaration: â€Å" Insert spreads within a given set of sequences in order to maximise a similarity standard † [ 24 ] . The MSA job can be divided into three troubles, which are scalability, optimisation, and nonsubjective map. Finding an accurate MSA from sequences is really hard. It is a clip consuming and computationally NP-hard job [ 13-15 ] . In fact, that complexness comes from that all three jobs must be solved at the same time. The first job is the scalability, which is to happen the alliance of many long sequences. The 2nd job is the optimisation, which is to happen the alliance with the highest mark based on a given nonsubjective map among sequences. Optimization of even a simple nonsubjective map is an NP-hard job. The 3rd job is the nonsubjective map ( OF ) , which is to rush up the computation in order to mensurate the alliance. Most modern plans for building multiple sequence alliances ( MSAs ) consist of two constituents: an nonsubjective map for measuring the quality of a candidate alliance of a set of input sequences, and an optimisation process for placing the highest scoring alliance with regard to the chosen nonsubjective map [ 25 ] . You read "Discovered Biological Functions Of Rna Health And Social Care Essay" in category "Essay examples" 3.0 Objective maps Aligning multiple sequences is a extremely non-trivial undertaking ( in both a biological and computational sense ) whose truth in pattern depends mostly on the pick of input sequences, the cost ( or aim ) map, and the heuristics employed [ 26 ] . An of import facet of alliance mark is to set up how meaningful a given multiple alliance is. This is to find whether the aligned sequences are in fact optimum and to gauge the mark of the alliance in which there is no anterior cognition of the mention alliance. Objective map is the psyche of iterative algorithms in the sense that it determines the campaigner move to be taken to better the solution quality. In multiple sequence alliance, nonsubjective map Acts of the Apostless as the cardinal factor to command the development of an alliance into a mature one. Using optimisation algorithm to work out any job requires delegating a fittingness map. In harmony hunt algorithm, this map evaluates and ranks harmoniousnesss in the harmoniousness memory harmonizing to their tonss. Harmonies that ain good alliance mark in the harmoniousness memory are retained. In this subdivision different nonsubjective maps are studied. The pick of nonsubjective map is strictly a biological job that lies in the definition of rightness. A mathematical map able to mensurate an alignment biological quality that defines a right alliance and its expected belongingss is called nonsubjective map ( OF ) . Given a perfect map, the mathematically optimum alliance assumes to be biologically optimum. While the map defines a mathematical optimum, it is seldom that this optimum will besides be biologically optimum [ 25 ] . There are different nonsubjective maps to hit the quality of the alliance, viz. sum-of-pairs, leaden sum-of-pairs, and NorMD [ 23 ] , MstatX, amd COFFEE [ 22 ] . They are used in optimizing and iterative alliance methods to better the alliance by seeking to maximise the nonsubjective map [ 27 ] . 3.0.1 sum-of-pairs Presently sum-of-pairs nonsubjective map is most widely used [ 28 ] . Carrillo and Lipman [ 29 ] foremost introduced the sum-of-pairs ( SP ) mark map, which defines the tonss of a multiple alliance of N sequences as the amount of the tonss of the N ( N-1 ) /2 pairwise alliances [ 29 ] , [ 30 ] . Although SP mark map has been widely used to measure MSA, it does n’t truly supply any biological or probabilistic justification [ 30 ] . Each sequence is scored as if it is descended from the N-1 other sequences alternatively of a individual ascendant. As a consequence, evolutionary events are frequently overestimated. The job worsens as the figure of sequences additions [ 30 ] the sum-of-pairs ( SP ) mark described in [ 31 ] , [ 32 ] , [ 29 ] , [ 33 ] is used to cipher the nonsubjective map ( OF ) where there is no anterior cognition of the mention alliance. The general signifier of OF mark of alignment n sequences consist of m columns is OF = . Where is the similarity mark of the column myocardial infarction, is the spread punishment of the column myocardial infarction and is the sequence length. The similarity mark of the column myocardial infarction can be measured by the sum-of-pairs ( SP ) . The SP-score S ( myocardial infarction ) for the i-th column myocardial infarction is calculated as follows: S ( myocardial infarction ) = , ( ) where is the j-th row in the i-th column. For alining two residues x and y, the permutation matrix s ( x, y ) is used to gives the similarity mark. 3.0.2 Weighted sum-of-pairs The leaden sum-of-pairs ( WSP ) score [ 28 ] , [ 34 ] is an extension of SP mark so that each pairwise alliance mark otherwise contributes to the whole mark. A leaden SP mark map has been proposed in the manner to reflect the relationships between the sequences. The rule is to give a cost to each brace of aligned residues in each column of the alliance ( permutation cost ) , and another cost to the spreads ( spread cost ) . These are added to give the planetary cost of the alliance. Furthermore, each brace of sequences is given a weight related to their similarity to other braces. The WSP calculates a entire mark from the leaden pairwise mark of all the sequences. The undermentioned figure shows the mathematical preparation of the leaden SP mark map. WSP ( A ) = ( ) Where N is the figure of sequences, k the length of aligned sequences, is the weight given to a brace of sequences, and is the similarity cost of two symbol sequence ( ) . The cost map included spread gap and extension punishments for gap and widening spreads. The weight of pairwise aligned sequences may be proportionately score [ 35 ] , [ 36 ] harmonizing to the sum of alone information enclosed in the sequence. These weights try to diminish the influence of excess information from strongly related sequences. A weight represents a per centum equal to a per centum individuality ( PID ) calculated over each brace of aligned sequences [ 24 ] as follows ( excepting spreads ) : PID = ( ) 3.0.3 Normalized Mean Distance normalized mean distance ( NorMD ) [ 23 ] is a normalized mean distance ( MD ) mark measures the normalized mean distance between the similarities of the residue braces at each alliance column, introduce in ClustalX, between similarities of residue braces at each alignment column. A mark for each column in the alliance is calculated utilizing the construct of uninterrupted sequence infinite introduced by [ 37 ] and the column tonss are so summed over the full length of the alliance. NorMD take into history the sequence information, such as the figure, length and similarity of the sequences to be aligned. NorMD is used in RASCAL [ 38 ] and AQUA [ 39 ] . 3.0.4 Consistency mark Consistency-based nonsubjective maps focus on improved marking of lucifers in early alliances by integrating information from of pairwise alliance. This consistence construct was originally introduced by Gotoh [ 40 ] and subsequently refined by Vingron and Argos [ 41 ] . Kececioglu [ 42 ] reformulated this job as a maximal weight hint ( MWT ) job. It was further expanded by Morgenstern [ 43 ] who proposed the first heuristic to work out this job for big cases. Consistency-based marking is used in T-Coffee [ 44 ] , MAFFT [ 45 ] , and Align-m [ 46 ] algorithms. The COFFEE [ 22 ] is a consistency-based which step optimized the figure of aligned residues that were besides aligned in planetary pairwise alliances of the same sequences. Coffee nonsubjective map which evaluates the consistence between a multiple sequence alliance and a antecedently defined library of pair-wise alliances. COFFEE required two constituents: ( I ) a set of pairwise mention alliance by utilizing any method for doing pairwise alliances, ( two ) the OF that evaluate the consistence between a multiple alliance and the pairwise alliances contain in the library. COFFEE plants by first bring forthing the pairwise library of the sequences in the alliance and so calculates the degree of individuality between the current multiple alliance and the pairwise library. COFFEE is non using excess spread punishments so that, it is non sensitive to the permutation tonss of amino acids, the mark is normalized, and the cost of similar braces is place dependent. Coffee is reflect the deg ree of consistence between a multiple sequence alliance and a library containing pairwise alliances of the same sequences. The planetary mark mensurating the quality of the alliance is computed by the undermentioned expression. Coffee mark = ( ) where Len is the length of the MSA ; Aij is the pairwise projection of sequences Si and Sj obtained from the MSA ; Wij is the per centum individuality between the two aligned sequences Si and Sj ; is the figure of residues braces that are shared between Aij and the pairwise. In add-on, utilizing chance in consistence leads to a alleged chance consistency. This hiting map is introduced in ProbCons [ 47 ] . It assigns position-specific permutation tonss based on a step of expected truth derived from a concealed Markov theoretical account. This thought is implemented and extended in the PECAN [ 48 ] , MUMMALS [ 49 ] , PROMALS [ 50 ] , ProbAlign [ 51 ] , ProDA [ 52 ] , and PicXAA [ 53 ] plans. 3.0.5 POsition-Specific and consIstency-based nonsubjective function ( POSITION ) POSITION [ 54, 55 ] is based on the consistence, it calculates the degree of individuality between the current multiple alliance and the pairwise library. The hiting map for POSITION is shown as under in Eq. ( 5 ) . POSITION = ( 5 ) where N is the figure of the sequences ; Aijl is the brace of residues at index cubic decimeter of the pairwise projection of sequences Si and Sj ; and Occurrence ( Aijl ) is a 0-1 binomial map of whether brace Aijl occurs in the pairwise library. W ( Aijl ) is the weight of Aijl and is assigned to the mean similarity of residue braces around index l. This is an attempt to specify the weight harmonizing to contextual information of residue braces. 3.0.6 MaxZ MaxZ is a statistical alliance quality mark introduced in [ 56 ] which first quantifies the grade of preservation at each alignment place and so counts the figure of significantly conserved places over the alliance. It used Zscore for mensurating the grade of preservation that is based on profile analysis [ 57 ] Then, by utilizing the importance trying method [ Using the SIR algorithm to imitate posterior distributions. ] , the statistical significance of an observed mark value is calculated. In footings of positional significance degrees, the full alliance mark is calculated. 3.0.7 MstatX MstatX calculates the trident statistic of each column in the multiple sequences alliance. Then by stipulate the statistic with the flag options. It can gives many different statistical steps on columns of a multiple alliance like Shannon information, frequence counts, spread counts, and more sophisticated marking. The default statistic is a weighted-entropy which means a Shannon information based on chances computed with the sequence burdening strategy defined by [ 58 ] . Statisticss proposed in MstatX is based on [ 59 ] and [ 60 ] . 3.0.8 Maximal expected truth ( MEA ) Maximal expected truth ( MEA ) [ 61 ] : The basic thought of MEA is to maximise the expected figure of â€Å" right † aligned residue braces [ 62 ] . It has been used in PRIME [ 63 ] , and ProbCons [ 47 ] algorithms. 3.0.9 Segment-to-segment nonsubjective map Segment-to-segment nonsubjective map: It is used by DIALIGN [ 64 ] to build an alliance through comparing of the whole sections of the sequences instead than the residue-to-residue comparing. 3.0.10 Profile mark Profile hiting map uses a marking map which is defined for a brace of profile places. In add-on to SP, MUSCLE [ 65 ] uses a new profile map which is called the log-expectation ( LE ) mark. Some of these nonsubjective maps integrated into other nonsubjective maps, each have its ain advantages and disadvantages. The nonsubjective map presently used in DIALIGN that is segment-to-segment nonsubjective map is flawed [ 66 ] . On the other manus T-Coffee is excessively memory demanding [ 12 ] . Sum-of-pairs is the most popular marking method because of its comparative velocity and hardiness. The velocity advantage is chiefly because the sum-of-pairs method does non necessitate a tree [ 67 ] . Some nonsubjective maps use permutations matrices whereas other used consistence construct by involve pairwise alliance. [ 68 ] disadvantage of these permutations matrices is that they are intended to rate the similarity between two sequences at a clip merely, and in order to widen them to multiple sequences, it is common to happen that they are scaled by adding up each pairwise similarity to obtain the mark for the multiple sequence alliance [ 5 ] . 4.0 Alignment Quality Q ( Quality ) is a quality map to gauge the comparing between the alliance and the mention alliance. Q mark is the figure of right aligned residue braces in the trial alliance divided by the figure of residue braces in the mention alliance. This has been termed as the developer mark [ 69 ] and SPS [ 31 ] . 5.0 MATERIALS AND METHODS Harmony hunt algorithm – which is out of range of this paper – is used to happen the optimal or a close optimum alliance harmonizing to the nonsubjective map. Given a perfect map, the mathematically optimum alliance will besides be biologically optimum. While the map defines a mathematical optimum, it is seldom have an statement that this optimum will besides be biologically optimum. two type of dataset are chosen ( I ) the subset of BRAliBase which are extremely variable and suited for local MSA ; ( two ) LocalEXtR, an extension of BRAliBase 2.1, consisting large-scale trial groups and patterned on BRAliBase 2.1 ; The series of experiments has been conducted in order to analyze the relationship of the corresponding nonsubjective map mark with the alignment quality. The experiment has been done in the term of correlativity coefficient between the nonsubjective map mark and the alignment quality mark in one side and the consuming clip in another side. First, the different nonsubjective maps are used as a fittingness map in HS algorithm and the relationship between them are studied. Second compare the quality tonss of 5 nonsubjective map utilizing database In pattern, it is hence ever recommended to utilize as many different methods. hence analysis did non curtail to merely a few of the best alignment methods but aimed to utilize as many methods as possible [ 12 ] . One of the primary challenges in sequence alliance is to happen a biologically meaningful nonsubjective map. A common pick of many alliance algorithms has been the ‘sum-of-pairs ‘ ( SP ) mark, which merely takes the amount of the tonss of all pairwise alliances in a given multiple alliance. To day of the month, there is no nonsubjective map that has been every bit good accepted for multiple alliances [ 70 ] as similarity has been for pairwise alliance. Alignment quality requires a mention alliance from database benchmark. The comparing is between the trial alliance and the mention alliance and it is called here alignment quality. Performance rating Two scenarios are done in different manner, The first scenarios, it uses an nonsubjective map in the HS Improvising procedure and analyze the relationship between the alliance mark with alignment quality for concluding alliance. This is repeated with all nonsubjective map. The motive for mark the alliance many times in every loop was the fact that alliances generated prior to the several iterative polish are frequently rather different from the concluding alliance [ 12 ] . Second scenarios, it measures alignment mark and alignment quality for the same alliance which is the concluding alliance by every nonsubjective maps individually. Alignment mark and its quality are compared for each alliance. This seneraio is to compare the consequence of different nonsubjective map on the same alliance These experiments to cognize how strong is the relation between them in each nonsubjective map individually. A comprehensive reappraisal of all methods will non be given here, but the common nonsubjective maps will be focus on. a. Harmony hunt algorithm Harmony hunt algorithm ( HS ) is developed by Geem [ 21 ] . HS is a meta-heuristic optimisation algorithm based on music. HS is imitating a squad of instrumentalists together seeking to seek the best province of harmoniousness. Each participant generates a sound based on one of three options ( memory consideration, pitch accommodation, and random choice ) . This is tantamount to happen the optimum solution in optimisation procedure. Geem et Al. [ 21 ] theoretical accounts HS constituents into three quantitative optimisation procedure as follows: first procedure, the Harmony memory ( HM ) : It used to maintain good harmoniousnesss. A harmoniousness from HM is selected indiscriminately based on the parametric quantity called harmony memory sing ( or accepting ) rate, HMCR ?„ [ 0,1 ] . It typically uses HMCR = 0.7 ~ 0.95. Second procedure, the pitch accommodation: it is similar to local hunt. It is used to bring forth a somewhat different solution from the HM depend on pitch-adjus ting rate ( PAR ) values. PAR control the grade of the accommodation by the pitch bandwidth ( brange ) . It normally uses PAR = 0.1~0.5 in most applications. Third procedure, the random choice: a new harmoniousness is generated indiscriminately to increase the diverseness of the solutions. The chance of randomisation is Prandom = 1- HMCR, and the existent chance of the pitch accommodation is Ppitch = HMCR A- PAR. The pseudo codification of the basic HS algorithm with these three constituents is summarized in Figure 1. Harmony Search Algorithm Get down Declare the nonsubjective map degree Fahrenheit ( x ) , ten = ( x1, x2, aˆÂ ¦ , xn ) Initialize the harmoniousness memory accepting rate ( HMCR ) Initialize pitch seting rate ( PAR ) and other parametric quantities Initialize Harmony Memory with random harmoniousnesss While ( t lt ; max figure of loops ) If ( rand lt ; HMCR ) , Choose a value from HM If ( rand lt ; PAR ) , Adjust the value by adding certain sum End if Else Choose a new random value End if End while Measure the solution by utilizing nonsubjective map Accept the new harmoniousness ( solution ) if better Update HM End while Find the current best solution in HM End Figure 1 Pseudo Code of the Harmony Search Algorithm [ 71 ] The HS algorithm has been applied to assorted optimisation jobs [ 72 ] that include Real-world applications, Computer scientific discipline jobs, Electrical technology jobs, Civil technology jobs, Mechanical technology jobs, and Bio A ; medical applications. B. Benchmark Dataset Three type of dataset are chosen ( I ) the subset of BRAliBase which are extremely variable and suited for local MSA ; ( two ) LocalEXtR, an extension of BRAliBase 2.1, consisting large-scale trial groups and patterned on BRAliBase 2.1 ; ( three ) Lset, a brace of large-scale trial sets representative of current biological job. The subset of the BRAliBase 2.1 are selected from the most variable dataset within the suite. They are from THI, Glycine riboswitch and Yybp-Tkoy RNA households, and contain 232 trial datasets. LocalExtR uses the same seed alliances from Rfam that BRAliBase uses and signifiers big trial groups. BRAliBase is label a trial group qi, where I is the figure of sequences for each trial set in the group. The tabular array ( 1 ) and ( 2 ) show the inside informations of the dataset and the description information about each trial set. Table 1: Trial Dataset Number of each Test Group trial Group gcvT Family THI Family yybp-ykoy Family BRALiBase 2.1 ( 232 datasets ) k5 22 69 33 k7 12 32 18 k10 3 17 12 k15 1 5 8 LocalExtR ( 90 datasets ) k20 10 10 10 k40 10 10 5 k60 10 10 0 k80 5 10 0 Entire 73 163 86 Table 2: Sequence length of each Test Group sequence length trial Group Avg. Min. BRALiBase 2.1 ( 232 datasets ) k5 109 96 k7 110 94 k10 108 94 k15 110 88 LocalExtR ( 90 datasets ) k20 115 90 k40 114 87 k60 107 81 k80 106 77 5.0 RESULTS AND DISCUSSION One chief challenge with MSA is how to gauge the quality of computer-aligned sequences. Therefore, an nonsubjective map ( OF ) is required in the optimisation processes. The pick of nonsubjective map and heuristics is critically of import in obtaining high quality alliances [ 12 ] . In add-on, OF acts an indispensable function in optimisation algorithms whereby the alliance is optimized against a mark computed by the OF [ 2 ] . The most straightforward OF is the sum-of-pairs ( SP ) score [ 3 ] , weight sum-of-pair [ ] , java [ 22 ] , Xstate [ ] and NorMD [ 23 ] . 5.1 Correlation between Objective maps Score and alignment quality Theoretically, an OF should ever give higher tonss for alliance with better quality [ ] . In world, nevertheless, since the nonsubjective map tonss and the alliance qualities are measured utilizing different standards, incompatibility happens. Correlation between alignment quality and different nonsubjective maps score were practiced on each experimental. Correlation coefficients ( R2 ) were so computed for each nonsubjective map and Q mark of the alignment quality. Two scenarios are performed to look into the correlativity the first one where utilizing the nonsubjective map as the HS Improvising procedure, the 2nd one where mark a concluding alliance by different nonsubjective maps. ( a ) First Scenario: utilizing the nonsubjective map in the generator procedure Five experiments are carried by utilizing an nonsubjective map and compared alignment mark with alignment quality in each experiment. Each experiment has been repeated 5 times for the same dataset and the norm is calculated. In this experiment, each nonsubjective map have been used individually as a fittingness map. Then, the correlativity of the nonsubjective map mark and the alignment quality mark is calculate utilizing the Correlation coefficients ( R2 ) . Each instance has been repeated 5 tallies for same dataset and calculated the norm for each nonsubjective map theoretical accounts. The figure of loop in each tally, is fixed in all the experimental in this experiment to 10,000. 322 trials set are used and their inside informations are summarized in Mistake: Reference beginning non found HS parametric quantities and others parametric quantities are setup to default puting for all nonsubjective map. Alliance Generator OF1 Alliance Mark |quality aˆÂ ¦ Alliance Generator OF2 Alliance Mark |quality aˆÂ ¦ In this experimental BHS-MSA is used to bring forth the alliance. Within the optimisation processes the nonsubjective map theoretical accounts, sum-of-pairs, weight sum-of-pair, java, Xstate and NorMD were used individually to give the good alliance quality. The concluding alliances were measured and evaluated by comparing with the mentions utilizing the rating map Quality ( Q ) and Entire column Score ( TC ) . The mean correlativity coefficient value of all dataset is listed and the spread secret plan graphs are listed as shown in Figure 2. shows the R indicated that the java and sum-of-pairs nonsubjective map has better positive correlativity with alignment quality than others does. The relation is positive that mean when the nonsubjective map is increase the alignment quality is increase this is clear shows in the Figure 3. Table 3: Correlation coefficients ( R2 ) of option Objective maps for scenario 1 SP WSP NorMD MstatX Coffee Correlation coefficients ( R2 ) 0.9216 0.7278 0.7613 0.8259 0.9642 fig 2 copy.jpg Figure 2: Scatter secret plan of alternate nonsubjective Functions for scenario 1 ( B ) Second Scenario: step a concluding alliance by different nonsubjective maps. In this experimental, 10 experiments are transporting out and alliance are bring forthing indiscriminately. Final alliance is measured by each nonsubjective map individually. Then, the correlativity of the nonsubjective map mark and the alignment quality mark is calculate utilizing the Correlation coefficients ( R2 ) [ 12 ] . This scenario is to back up the old 1. The correlativity on different nonsubjective map on alliances is study here by another manner where the nonsubjective maps are step the same alliance together and the relationship between the alliance mark with alignment quality are studied individually for each nonsubjective map. For ocular review, matching spread secret plans for all nonsubjective maps are presented. Alliance Generator OF1 Alliance Mark |quality aˆÂ ¦ aˆÂ ¦ aˆÂ ¦ OF2 Mark |quality aˆÂ ¦ aˆÂ ¦ aˆÂ ¦ HS and MSA parametric quantity are fixed to same values in all experimental. The mean correlativity coefficient value of all dataset is listed in Table 4 and the spread secret plan graphs are shown in Figure aˆZ3 Table4 shows the R indicated that the java and sum-of-pairs nonsubjective map has better positive correlativity with alignment quality than others does. The relation is positive that mean when the nonsubjective map is increase the alignment quality is increase this is clear shows in the Figure aˆZ3 Table 4: Correlation coefficients ( R2 ) of option Objective maps for scenario two sum-of-pairs ( R ) wsop ( R ) NorMD ( R ) Xstat ( R ) Coffee ( R ) Correlation coefficients ( R2 ) 0.8319 0.7558 0.6762 0.8028 0.9494 fig 3 copy.jpg Figure aˆZ3: Scatter secret plans of alternate nonsubjective maps for scenario two 5.2 Study of Coffee and SP Objective maps based on clip cost Objective map is the most computationally time-consuming constituent of MSA alliance method. The clip complexness of calculating an nonsubjective mark additions linearly with length of alliance and the figure of sequences. Figure aˆZ shows that increasing the sequence figure lead to increase the clip cost for calculate the nonsubjective map for the java and SP nonsubjective maps. Table5: Time cost of each Test Group Test Group No. of Seqs. sequence length Avg. Time Avg. min soap SP BRALiBase 2.1 ( 232 datasets ) k5 5 109 96 125 0.16 k7 7 110 94 131 0.32 k10 10 108 94 129 0.66 k15 15 110 88 137 1.60 LocalExtR ( 90 datasets ) k20 20 115 90 172 3.52 k40 40 114 87 180 16.96 k60 60 107 81 189 42.72 k80 80 106 77 204 88.01 Based on the correlativity shown in 4, the correlativity between the alliances hiting and the alignment quality utilizing the COFFEE nonsubjective map and sum-of-pairs were better than those found utilizing the NorMd, MstatX, and WSP nonsubjective maps. Coffee and sum-of-pairs nonsubjective maps have the highest correlativity. Based on the clip cost shown in Table5: Time cost of each Test Group and figure 4, the cost clip used by sum-of-pairs is better than java nonsubjective map for all trial groups. Figure aˆZ4: Coffee and SPS Objective map clip 6.0 Decision The alliance of multiple sequences remains a challenging job today. Here, we do non discourse possible schemes to better alliance quality, but alternatively concentrate on the maps used to measure the quality of completed alliances. The relationship of the alliance mark and alignment quality of different nonsubjective map is the aim of this paper. It is recommended to run several maps and compare their consequences to happen the most suitable one. The consequence shows that the correlativity between the alliances tonss and the alignment quality utilizing the COFFEE nonsubjective map and sum-of-pairs were better than those found utilizing the NorMd, MstatX, and WSP nonsubjective maps. Coffee and sum-of-pairs nonsubjective maps have the highest correlativity. It besides shows that the alliance marking by sum-of-pairs is better than java nonsubjective map for all trial groups in footings of consuming clip The tonss produced by sum-of-pairs and java are better correlated to the existent alliance truths than tonss produced by other methods. 7.0 Recognition The writers would wish to appreciate the School of Computer Sciences every bit good as University Science Malaysia for their installations and aid. The writers are appreciative of the attempts of the referees for their helpful remarks. How to cite Discovered Biological Functions Of Rna Health And Social Care Essay, Essay examples

Sunday, May 3, 2020

Principle of Capital the Maintenance †Myassignmenthelp.com

Question: How Do To Principle of Capital the Maintenance? Answer: Introducation The principle of Capital maintenance postulates that a firm must receive proper compensation for its shares and must not repay it to the shareholder except under exceptional situations. Profoundly, this doctrine was first developed in the mid-19th Century in the United Kingdom (Kaplan, n.d.). Today, this doctrine has become less relevant in the contemporary business world. Most companies have a relatively small share capital and consider the capital maintenance regulations as unduly complicated. Others argue the rules of the principle have been overtaken by their exceptions. As a result, various countries such as Singapore, Australia, and the UK, and have restructured their capital maintenance guidelines over the past years to suit their specific needs. In Trevor v Whitworth, a firm purchased most of its own shares. During its termination, one member applied for the balance of funds that the company owed him after the purchase. The court ruled that he should be compensated (Islam, 2013). Contrariwise, The House of Lords argued that the purchase was void, declaring that the business cannot buy its own shares despite the fact that there was a provision for that in the companys memorandum. It also held that there could be no refund of funds to the shareholders other than on an appropriate reduction of capital authorized by the court. Thus, this case law applied the rule that stipulates that on the liquidation of a firm, members can retrieve their money only after all creditors have been reimbursed. Benefits of the doctrine Fundamentally, the benefits of the doctrine lie in the fact that it sought to safeguard the interests of creditors. In addition, it aimed at ensuring the lawful utilization of the assets of a business. Markedly, this principle has developed through a sequence of judicial interpretations in company case law. For instance, in the Flitcrofts Case, Jessel M. R. incidentally stated some aspects of this rule (Islam, 2013). First, the creditors have a right to ensure that the funds of a business are not used improperly. It also highlighted the fact shareholders should not be refunded their capital secretly. Here, the case was argued on the basis of the rules of capital reduction and company distributions. Exceptions to the doctrine It is imperative to note that there are certain exceptions to the doctrine of maintenance of capital. In Bangladesh, the rule on the reduction of capital proposes that a firm that is limited by shares does not possess the right to purchase its own shares or those of a public firm unless the consequent reduction is effected and sanctioned as per the requirements set out in sections 59 to 70. With regards to the purchase of shares, a company limited by shares cannot purchase its own shares except if it follows appropriate measures as outlined under Companies Act of 1994 (Hannigan, 2012). Likewise, in England, exceptions have been made pertaining to the reduction of share capital. The CA 2008 allows private companies to condense their capital through a special resolution reinforced by a statement of creditworthiness issued by all the managers. Reference List Capital maintenance. Kaplan Financial Knowledge Bank, [online]. Available at https://kfknowledgebank.kaplan.co.uk/KFKB/Wiki%20Pages/Capital%20maintenance.aspx [Accessed 21 May 2017]. Chapter 3: Capital maintenance. Cr.gov, [online]. Available at https://www.cr.gov.hk/en/publications/docs/062008_ch3-e.pdf [Accessed 21 May 2017]. Hannigan, B., 2012. The doctrine of capital maintenance. Oxford Index, [online] (Last updated June 2014). Available at https://oxfordindex.oup.com/view/10.1093/he/9780199608027.003.0020 [Accessed 21 May 2017]. Islam, S., 2013. The Doctrine of Capital Maintenance and its Statutory Developments: An Analysis. The Northern University Journal of Law, 4, pp. 47-55.

Tuesday, March 24, 2020

Proper Role of Government free essay sample

Describe the government and domestic environment of the country where your company is headquartered, then describe the international environment. Outline what organizations you may be associated with. (Example; WTO, OPEC, etc. ) Examine the 1st  country of International growth you outlined in your 10 year vision. Why did you strategically select that country? In what ways will your company contribute to the foreign country’s economic development? Are there any political concerns associated with expansion into this country? Why or why not? How do you plan to develop a good working relationship with the foreign country? Put together a SWOT analysis for your company. (This is considered an exhibit) Put together a PEST Analysis (exhibit) for the country you identified as the country into which your initial global expansion will take place. While maintaining its relationship with the United States, Japan has diversified and expanded ties with other nations. Having good relations with its neighbors can be a vital interest. We will write a custom essay sample on Proper Role of Government or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page Japan extended significant economic assistance to the Chinese in various modernization projects and supported Chinese membership in the World Trade Organization (WTO). AIG† Japan contains in depth information and data about the company and its operations. The company contains an overview, business description, financial ratios, SWOT analysis, key competitors, key facts, key employees, locations and branches as well as information on products and services. The SWOT analysis the company profile can be crucial for the industry executives and anyone looking to gain a better understanding of the company’s business. So, the SWOT Analysis utilizes a wide range of primary and secondary sources. As learned from reading the chapters and from the PowerPoint slides, SWOT is an abbreviation for the internal Strengths and Weaknesses of a firm and the environmental Opportunities and Treats facing that firm. SWOT analysis is a widely used technique through which managers create a quick overview of a company’s strategic situation. The technique is based on the traditions that an effective strategy derives from a sound â€Å"fit† between a firm’s internal resources (strengths and weaknesses) and its external situation (opportunities and treats). A good fit maximizes a firm’s strengths and opportunities and minimizes its weaknesses and threats. Accurately applied, this simple assumption has powerful implications for the design of successful strategy. AIG (American International Group) is one of the world’s leading insurance and financial services organizations, with operations in more than 130 countries. With a market capitalization of like $200 billion, AIG is like in the top ten most company in the world. AIG’s subsidiaries are leading providers of retirement services, financial services and asset management around the world. The group was the second largest insurance group in the world after China Life Insurance. SWOT (Strength, Weaknesses, Opportunities and Threats) Location| Types of Factor| | Favorable| Unfavorable| Internal| Strength * Global leading provider of financial services * Expanding global reach * Diversified product portfolio and new product development * Corporate advertising and brand building sponsorships| Weaknesses * US residential mortgage market exposure * History of regulatory investigations * Declining cost efficiencies | External | Opportunities * Acquisitions * Growth in asset management industry| Threats * US recession and volatility in financial markets * Industry consolidation| Japan has faced a number of external challenges over the long term, most of which relate to the rising importance of China and the associated threat to Japans pre-eminent political and economic position in the Asia region. The countrys long-term outlook is also strongly influenced by its demographics. Current trends indicate that the rate of decline in the working-age population will outpace that in the population as a whole. On the positive side, in 2021-30 Japan will see an increase in its rate of GDP growth per head to 1. 7% a year, from around 1% a year in the first two decades of the century. Productivity growth will also accelerate in the latter part of the long-term forecast period. The environment has some current issues with the air pollution from power plant emissions results in acid rain; acidification of lakes and reservoirs degrading water quality and threatening aquatic life. Japan is one of the largest consumers of fish and tropical timber. | 2012-20| 2021-30| 2012-30| Growth and productivity (% change; annual av)| Growth of real GDP per head| 1. 5| 1. 7| 1. 6| Growth of real GDP| 1. 0| 1. 0| 1. 0| Labour productivity growth| 1. 9| 1. 8| 1. 8|

Friday, March 6, 2020

Censorship s essays

Censorship s essays Censorship, so far as I see it, is like a law which prohibits swimming altogether because such a law will prevent someone from swimming in a sewer (Brower 1). Here, in the twenty- first century, the banning of thoughts and ideas in humanities and media has become one of the most widely disputed issues facing this country. Though it is highly controversial, hazardous to literature, and unconstitutional, censorship is rampant in America. Censorship is defined as Policy of restricting the public expression of ideas, opinions, conceptions, and impulses, which have or are believed to have the capacity to undermine the governing authority or the social and moral order which that authority considers itself bound to protect (Abraham 357). There is said to be four different categories, which are referred to as political, religious, against obscenity, and censorship affecting academic freedom. All of these categories are equal in their destructiveness towards free speech. There are two different forms that censorship takes; prior, which refers to advance suppression and post facto which is suppression after it has been published (Brower 5). Authorities since the beginning of the written word have used both of these forms of censorship. Throughout history, figures that dont have the real power to censor resort to personal pressure tactics to intimidate those who have influence over, or in command of, channels of communication. The McCarthy era during the 1940s and 1950s is a compelling example of this. During this time there was blacklisting of controversial literary figures as well as performing artists, thus blocking their employment in certain media such as movies, radio, and television. By doing this they accomplished the task of preventing the public from seeing what they considered to be objectionable material (Dubin 27). There are many rationalizations that are use...

Wednesday, February 19, 2020

3. Identify some examples of West Afrian heritage or survivalisms Essay

3. Identify some examples of West Afrian heritage or survivalisms among African Americans - Essay Example African heritage among African Americans is the Black Arts Movement as a cultural explosion to witness the incorporation of the surviving cultural attire with contemporary fashion elements and the traditional clothing of the West Africans. This led to the development of a traditional style which was uniquely African-American. The most popular African textile is Kente cloth. Originally, the Ewe and Ashanti peoples of Togo and Ghana used to make such festive woven patterns. Kente fabric can be seen in different fashions of the West Africans including casual t-shirt, cummerbunds, and formal bow ties. African Americans have been wearing the traditional African clothing both formally and informally since the commencement of the Black Arts Movement. Vibrant colors, trade beads, mud cloth, and jewelry and couture made with Adinkra motifs are other manifestations of the commonly witnessed traditional African dress elements in the African American culture. Another aspect of fashion commonly f ound in the African American culture is use of appropriate dress for worshipping. In most Black churches, people are expected to present themselves in the best possible way for

Tuesday, February 4, 2020

Preperation of mentorship level 3 ( degree level) Essay

Preperation of mentorship level 3 ( degree level) - Essay Example The portfolio is not only used as evidence but also has effective learning tool. This pattern of learning is an approach rooted and based on the principles of experiential learning2 which is cyclical process of recording, reviewing and ultimately learning from events3. It is highly important that enough attention is provided to ensure the portfolio is not just a collection of event narratives but includes reflections on these events and the lessons learnt in the process. Any evidence of learning is captured in the portfolio as evidence that reflective learning has taken place. In compliance with the guidelines for the completion of the portfolio, we consider a few key assumptions for the purpose of this document. The attempt will be to integrate theory and practice to ensure the portfolio of learning will establish how the learning outcomes are achieved by this exercise of portfolio document While we are aware that the concept of Portfolios are not new, it is important to acknowledge the fact that their use in initial and continuing professional development in medicine is still in its infancy and premature stage. In this context, the attempt here has been to achieve the following aims and objectives: There is no focused attempt to address the particular constraints or resource issues that face practitioners in any educational initiative, as these are far too many and too complex for a document of this type and nature keeping in view the existing limitations. However, it does provide evidence of a range of ways in which opportunities have been created and developed by colleagues and other interested parties in establishing frameworks and mechanisms within which individual learning can be planned, appropriately documented and effectively assessed. Portfolios certainly have much to offer both learners and teachers as we move forward into the new world of revalidation, clinical

Sunday, January 26, 2020

Fire Fighters Community Heroes English Language Essay

Fire Fighters Community Heroes English Language Essay Firefighters are a symbol in a community of hope and protection. They are there whenever you need them for most happenings. To be a firefighter means you have to be fearless and show tremendous courage. I believe I have the great amount of courage that is required. Courage however is not the only characteristic required to be a firefighter. To be a firefighter you must also be selfless and have an enormous awareness of the community. I choose this job because I feel it most fits my personality and since I was a child wanted to become a firefighter. I intend to learn the requirements and amount of training that is needed to be a firefighter. I have talked to many firefighters that work for the Melbourne Fire Department and they basically told me that this job is not easy. It requires a strong mental balance and you must keep your cool in stressful situations while dealing with that fire around them. Also they explained to me that this job is not just a normal job. It has long and irre gular hours that most cannot deal with. There is a benefit to those long hours though. If you accumulate enough hours and work more than your supposed to they are required to pay you overtime which can put extra cash in your pocket every pay check. While exploring jobs I encountered many jobs that interested me. But one I seriously considered was being a teacher. I would inspire to become a math teacher. I am very skilled at math and have a can do attitude. The only reason I did not choose this job as a primary career was because it required too much schooling and it didnt pay enough. In between my shifts I would like to be a substitiute teacher. To have the requirements for applying to be a firefighter is not hard. Most have a high school degree, but you can go to a community college and get an associates degree in fire sciences and be over-qualified for the job, which increases your chance for employment. Some colleges even have 4-year degrees in fire engineering. As of lately, many of the new firefighters are going to those universities that offer such educational opportunities, to acquire those degrees, then applying for the job (BLS). To officially become a firefighter is a long process. First your application must be chosen. If your application is chosen then you are required to go to a training facility for a couple weeks and be schooled about firefighting techniques, procedures, and codes. When at this training you will learn how to use equipment such as: axes, chain saws, fire extinguishers, ladders, and other fire fighting and rescue equipment. After attending the training and passing it, you will be placed on a probation period. Some fire departments have accredited apprenticeship programs that can endure up to 4 years. These programs merge strict instruction with on-the-job training while under the supervision of an experienced fire fighter. One thing all departments have in common is that in order to become a firefighter you must be a certified emergency medical technician. To become an EMT (emergency medical technician) you must apply to a training seminar. To apply you must have a high school degree. The re is no need for further educational schooling to have your application selected. There are three levels of training; Basic, Intermediate, and EMT-Paramedic. Most departments accept the lowest level. If you are employed at a larger department, like in a big metropolitan area, they may require you to have a paramedic certificate along with the EMT training. This means you are to take the most advanced level of training. Some of the departments add the EMT training into their fire schooling, but others may allow an employee to do it on their own time and give them a year to do so. Many fire departments would like for their firefighters to go to the training sessions supported by the U.S. National Fire Academy (BLS). Departments either reimburse the employee for the training or give them a higher pay because of their advanced training. Along with all of the certification involved, you must take a written exam, physical exam, and a medical exam. The physical exam tests you in: stamina, coordination, agility, and strength. The medical test consists of a drug screening and examination of body. Employees may be randomly drug tested at anytime during employment. Those who pass all the tests with the highest scores have the best chance of being hired (BLS). The skills required to become a firefighter is a long and dreadful list. You must have these skills: mental alertness, self-discipline, courage, mechanical aptitude, endurance, strength, and decision making skills. Decision making is an important skill because you are constantly under a lot of pressure and in life and death situations. If you dont make a decision quickly you could find your self dead or one of your co-workers trapped inside a burning building. I believe I have those qualities to become a firefighter. I have performed acts of those qualities in pressure situations when I was the head of a group of challenged individuals. A person who is suited for this job must have personality traits that benefit the department and not him. For example someone who is not a team player and has no teamwork can put himself or his team in danger if he does not communicate properly or adequately. Someone who has a good sense of teamwork, can lead his team through a burning building by pro perly communicating and having a sense of awareness about the surroundings. Also a firefighter must have respect because while he is on duty he is living with his crew and must respect their persons and their personalities. To be a firefighter means a lot in a community. It means you are the protector of all those whom live in the community. Teamwork is essential to any team that is functional and well-working. I can exhibit a great deal of teamwork while at work and in my community. Being a firefighter is not a good way toget rich quick. Being a firefighter is more of a morally awarding job. The average earnings of a firefighter are $41,600 in local government, $41,070 in the Federal Government, and $37,000 in State governments (BLS). As you can see it is more promising if you work for a local government. You can earn more than your salary though by working overtime. They can earn overtime by working more shifts to cover minimum staff levels and working during special occasions such as natural disasters and national emergencies, i.e. September 11th. There are many levels of employment in a fire house: Fire chief, Deputy Chief, Assistant fire chief, Battalion chief, Fire prevention/code inspector, Fire captain, Fire lieutenant, and Engineer. They all make different levels of pay but the highest if the Fire chief. At the highest level of pay he can make at most $95,271. The minimum salary for a fire chief is $73,435. The base level in a fire house is an Engineer. The maximum base salary for an Engineer is $56,045. The minimum salary is $43,232 (BLS). The benefits for a firefighter are very nice. They usually are given medical and liability insurance, vacation and sick leave, and paid holidays. In addition to these benefits, they dont even have to pay for their equipment. The local, federal, or state governments pay for them. They are covered usually by pension plans that allow them to retire after 25 years and receive half pay. This also covers them if they are disabled while working. The reason they receive such good benefits is because the heath hazards involved in the job are limitless. They are constantly dealing with smoke which can cause asthma or lung cancer. The most common killer of firefighters is the heart attack. The risk of having a heart attack increases 100 times when a firefighter is battling a blaze. 32% of firefighter deaths by heart attacks happen while at a fire scene. Being employed as a firefighter can be a difficult thing if you are looking to be employed by a federal or state government. About 90% of employments of firefighters were by local governments. This means that if you are looking to become a firefighter you should apply to become a firefighter in your local community. There is however competition. Volunteer firefighters are the trained firefighters enemy. They work for free and take the positions of a schooled firefighter. In the next ten years there is expected to be a 12% increase in firefighters (BLS). This means that competition isnt slowing down anytime soon. In fact it is only getting stronger seeing that the newer, younger firefighters are becoming better schooled and getting degrees. Most of the increase will come from the conversion of volunteer firefighters to paid firefighters. The competition for this job will never go away due to that fact that the number of applications outweighs the number of positions available. A typical day for a firefighter starts at 8 a.m. They then change into their uniform to relieve the on duty personnel. They check their gear before they do anything else. Once they have checked their gear thoroughly they then prep the fire truck and ready their gear in case of action. During the day they will respond to many calls. While on duty a firefighter must have one-hour of completed physical activity. Every house has gym equipment in it for that reason. They may be called to do other services such as: fire hydrant inspection, car seat installations, and planning for fires. A firefighters usual shift last about 24 hours. They do many odd jobs and respond to many emergency fires. Through my research I have realized I am well suited for this job. I have learned that it take guts and a lot of courage to do this job. Also that it is not only just fires you deal with. You may deal with medical emergencies and hazardous spills. Being a firefighter is a tough job but I believe that I have the nerves to deal with such a stressful job. Not may people can do this job effectively. I believe I can. I have concluded that firefighting would be a dream job of mine because one of my many passions is fire. I am obsessed with fire and its properties. It is very dangerous but being a firefighter would train me to become a certified professional fire handler. I would like to in the future experience the rush a firefighter gets when he/she gets a call and is on the go. It must be confusing feeling, focused yet nervous. In my future I am going to be a firefighter/substitute teacher. http://www.msnbc.msn.com/id/17695966/ns/health-heart_health/ http://www.job-employment-guide.com/firefighter-average-salary.html http://www.bls.gov/oco/ocos158.htm http://www.bls.gov/oco/ocos101.htm http://www.vbgov.com/vgn.aspx?vgnextoid=75ceede97c04c010VgnVCM1000006310640aRCRDvgnextchannel=72fdfd67f3ad9010VgnVCM100000870b640aRCRDvgnextparchannel=60ddfd67f3ad9010VgnVCM100000870b640aRCRD

Saturday, January 18, 2020

DBQ for AP United States History Essay

Britain’s taxation on the American colonists greatly affected the relationship between the two nations. Moreover, the colonists were not being represented. The feeling of deprivation not only angered the Americans, but may have also opened their eyes to see the need of a revolutionary movement. Thomas Jefferson states in A Summary View of the Rights of British America that they â€Å"possessed a right, which nature has given to all men.† The British deprived the colonists of these rights when they did not allow a representative in the House of Commons, as decided in the Resolutions of the Stamp Act Congress of 1765. This was especially unfair for the colonists for they were not only being taxed, but also received nothing in return for their own benefit. Additionally, the taxes did not profit the colonist itself. Rather, all tax profits went to Britain. It was a way for the British to reimburse the financial debts from the Great War for Empire. Taxation on the colonists was a way the British â€Å"liquidated its war debt,† as stated in Document N. As said in the Declaration of the Causes and Necessity of Taking Up Arms (Document I), The colonists did not give consent to Britain to take away their money by exploiting the land by heavy taxes. They felt that only they had the power and the right to tax themselves. As new heavy taxes piled upon each other, the colonists realized even more the need of an outbreak from Britain and the destruction it has brought upon the colonists. Thomas Paine explains in Common Sense that â€Å"there is something very absurd in supposing a continent to be perpetually governed by an island.† Paine is saying that a small island like Britain cannot rule a big continent, as a small child cannot rule grown adult. The author of the Stamp Act and former Prime Minister George Grenville states that Great Britain’s intention is to protect America and nothing more. By doing this favor, he believes America should yield to British authority and practice obedience. Thomas Paine rebuttals and argues that only small islands that are incapable of protecting themselves should be the ones who are taken under a kingdom’s care. Paine believes that this is not the case for the colonists. He sees that America is not a small island in need of help. Rather, America is â€Å"geographically secure, politically mature, prosperous, dynamic, and self-reliant,† as Lawrence Henry Gibson states in Document O. Thomas Paine also calls for a move towards democracy. The American people could no longer live under the bondage of British authority, which stripped them of their natural rights. Britain, for example, â€Å"deprived [the colonists] of the accustomed and inestimable privilege of trial by jury,† (Document I) which they claimed to have violated their life and property. Document L illustrates of the austerity of British rule. A woman lay on the ground naked and distressed, while British officials watch with pleasure. Surely, they had to respect for the motherland’s offspring. Clearly, this is not a way to show that the British protected and cared for the colonists as George Grenville previously stated when he spoke on Repeal on January 14, 1766. Because of unequal treatment, the American desire for equal representation grew the more. The unfair treatment of the British to the Americans only pushed the colonists to their limit. Taxation without any representation, or benefits in return truly raised an issue of equality. The British has suppressed the colonists. Weary of this, the colonists moved towards a revolutionary movement, wanting to escape the British Crown and authority, but all the more, where they would take up on democracy in which they could practice equal representation.

Friday, January 10, 2020

Manufacturing Technology Essay

In this article, it lists out several manufacturing technologies that set out new and easier processes for not just the workload, but set for an easier lifestyle as well. (summary) The automated systems was best said on my end. Transfer machines, cell phones and other automated devices are used to set a communication establishment upon anyone. It’s all about producing faster and having more efficiency in the industrial world. They also help reduce costs such as a bank you have ATM’s rather than having a clerk or 2 handling your withdrawals and deposits. You also have development of apps. These apps can take pictures of your checks and deposit them from there. Also manage your accounts with transfers and payments. It’s claimed that many human interactions really don’t require the human touch to it, which is true. Transfers of virtual products and or cash don’t need to be manually human handled. The article has been developed this year, which defiantl y will have a fair and accurate perspective on the manufacturing technology that we have in mind now. Timings, R., & Wilkinson, S. (2000). Manufacturing Technology (2nd ed.). 1061-2890, Harlow, Essex: Longman. In this book we come across specific detail about percentage-wise wholes in how much costs were reduced at the time of the startup in manufacturing technology. It claimed that all manufacturing technology orders dropped 20.4% at the start of its creation and then suddenly rose 9.8% later that year. Every year since then there’s been a 3% up raise since the start of it all. Having it being written 15 years ago I am heavily against this book, just due to the fact of how much our technology has advanced. The book shows how transfer machines are being held against in the workload and reducing the efficiency of work from its employees which is just a big key factor in communication. With the advancement in technology this has got to be a joke. Almost all technology is set in touch screen adaptations, faster ram processors, and larger memories to keep companies moving and cost efficient. Blaedel, K. L. â€Å"SciTech Connect: Manufacturing Technology.† SciTech Connect: Manufacturing Technology. USDOE, 1 Feb. 1997. Web. 20 Jan. 2015. This set article claims that there are 4 projects that led to the main movement of manufacturing technology. It details exactly how they got to developing such a vast movement at the time which we could easily set apart from our age having it being published over 10 years ago. It shows exactly how to â€Å"develop an understanding of fundamental fabrication process†. Heap, J. (2004). International Journal of Productivity and Performance Management (Vol. 57, pp. 156-176). Bradford, England: Emerald Group. This book had several findings of out SME’s had an early development progress against productivity and performance management throughout different AMT’s. It shows the different effects in management and what manners they had at the time to reduce operation costs and team efficiency. Acquisition of Manufacturing Technology. (2013). MENA Report, Retrieved from http://search.proquest.com.ezproxy.libproxy.db.erau.edu/docview/1419103734?accountid=27203 Throughout this article we the write to see what acquisitions were involved to establish the different types of manufacturing technology in our more recent industry. Our updated technologies have claimed to make our recent years more cost efficient and productive by over 150%! I am all up with this article because it has its cited facts and it’s only 2 years from our current date, so this would be my most supported article just due to the date it was created. Milgrom, P., & Roberts, J. (1990). The Economics of Modern Manufacturing: Technology, strategy, and organization. The American Economic Review, 511-528. In this scholarly article, we learn the economics of modern manufacturing and what came with the update at the time and how it was processed and underwent a revolution. The scholarly article stated that the â€Å"mass production model is being replaced by a vision of a flexible multiproduct firm that emphasizes quality and speedy response to market conditions while utilizing technologically advanced equipment and new forms of organization.† This was the start of a new branch in observing what could be replaced and updated with technology. I do enjoy seeing the central difference of how technology has shaped the workplace with time. Doms, M., Dunne, T., & Roberts, M. J. (1995). The Role of Technology Use in the Survival and Growth of Manufacturing Plants. International Journal of Industrial Organization, 13(4), 523-542. In this scholarly article, we come to distinguish the relationship between principal strength, how we use to come across the usage of manufacturing technology and what growth rates it came with. It stated that the main findings at the time had a mindset of higher progression rates against technology would have a far less development and production failure. Tracey, M., Vonderembse, M. A., & Lim, J. S. (1999). Manufacturing Technology and Strategy Formulation: Keys to Enhancing Competitiveness and Improving Performance. Journal of Operations Management, 17(4), 411-428. When coming across this article we see how the main set of technology was set and how that generation at the time had evolved it into a more competitive and healthier implement. As stated, â€Å"Linear Structural Equation Analysis results show that the relationships between a firm’s practices in these two areas and its competitive capabilities are found to be statistically significant and positive†, which shows me they had their own strategic role in which they followed to test out their performance and which ways they could use to improve the marketing satisfaction. Shepherd, D. A., Mcdermott, C., & Stock, G. N. (2000). Advanced Manufacturing Technology. Journal of High Technology Management Research, 11(1), 19-33. doi:10.1016/S1047- 8310(00)00019-5 We come to the instruction of AMT’s and how their benefits improved our workload and consumer satisfaction. This article shows the specific studies in how AMT’s were tested and outweighed the beneficial manufacturing firms in all over the world. The flexibility and higher efficiency claims from them outsourced many operational downfalls to provide advantage across the marketplace. Cho, K. (1993). Manufacturing Technology in Korea. Journal of Manufacturing Systems, 12(3), 216-222. doi:10.1016/0278-6125(93)90331-M Set across this article we have a different perspective having most of us live in the United States. With 32 set studies across this article it has been set that they have had an establishment of implementing local manufacturers across the nation with the support of  education al programs in technology and engineering. A different set perspective against the U.S. showing us how other countries had a different goal with maintaining manufacturing technology. Anonymous. (2011, ). TECHNOLOGY MANUFACTURING HEALTH CARE. Daily Herald (Arlington Heights, IL) This article was interesting to me to see the perspective of how manufacturing technology affected the health care industry. With 2 new hospitals opening up in other countries, hospitals have set out ads over the radio and television to help drivers understand the dangers of texting while driving and the rising amount of drivers ending up in the hospital from being distracted behind the wheel. I did enjoy reading this because I do commute 80 miles a day to work on the highway and easily see how much people are distracted behind the wheel. I wouldn’t know this new advancement in technology has caused such an uprise in car accidents, enough to open new hospitals around the world.

Thursday, January 2, 2020

Why Animal Cruelty is Horrible - Free Essay Example

Sample details Pages: 2 Words: 584 Downloads: 8 Date added: 2019/05/16 Category Society Essay Level High school Tags: Cruelty To Animals Essay Did you like this example? Imagine you are being experimented on. Your skin burns, everything hurts and you have no way to stop it or to get help since you can’t speak. Imagine you are being tortured, starved, beaten, and many more unimaginable things by someone who was supposed to care for you and love you. Don’t waste time! Our writers will create an original "Why Animal Cruelty is Horrible" essay for you Create order Unfortunately all these things happen to millions of animals each year in the form of animal cruelty. Animal cruelty can be defined as the crime of inflicting physical pain, suffering or death an animal. Animals live, breath and feel like we do, they have beating hearts like we do so what makes us better than them? I am Here today to make you all aware of how horrible and disgusting animal cruelty is and why it has to be stopped. I will be discussing the different types of animal cruelty, animal testing, and why animal cruelty has to be stopped. There are several different types of animal cruelty that many people don’t know about. When someone mentions animal cruelty most people’s minds go to starved animal left out in the cold but that’s just one type of abuse.Other types include things like forcing two animals to fight to the death. Those animals, usually dogs and roosters, die a very painful death and all for the entertainment of those horrible people. Animals are being slaughtered in the most horrible and painful was so that people could eat them. Statistics show that an estimated 12,570 animals are being treated cruelly every day in Australia alone. The statistics also show that a large number of the abusers are men under the age of 30. (Humanesociety.org) A lot of people in society don’t truly realise how serious of a problem animal testing is. Animal testing happens all over the world and some people are just encouraging it by buying products that were tested on animals. Do these people not realise that those animals are suffering on a daily basis due to animal testing. According to DoSomething.org more than 115 million of different species of animals are killed every year from the experiments that are being performed on them in a lab. Why are all these animals being tested on, murdered and yet we still haven’t done anything to ban this forever everywhere? Right now in this very moment there are millions of animals stuffed into tiny cages in labs all around the world, longing to be freed just dreading about the next painful procedure to be done on them. There are many reasons why animals cruelty has to be completely abolished. They can’t speak up for themselves that is why it’s our duty to speak for them and not allow them to be hurt any longer. We talk about equality a lot yet these animals aren’t treated with the equality that everything with a beating heart deserves. Animal cruelty is a horrible, nauseating crime and those people killing animals are really no different from murders. All these points that I have made such as the different types of animal cruelty, why animal testing is terrible, and why animal cruelty should be abolished completely makes you really think about how horrifying animal cruelty is. It makes you think a lot about the horrible lives these animals live while just waiting for their death. Animal cruelty is not something one person can change. It takes so many more people to help these poor defenseless creatures. Animal cruelty MUST be stopped!